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10 Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.9 Division of Biologics Review and Research 3, Office of Biotechnology Products, Center for Drug Evaluation and Research, US FDA, Bethesda, MD, USA.8 Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

7 Division of Genetics and Metabolism, Children's National Hospital, Washington, DC, USA.

6 The Children's Hospital of Philadelphia, Division of Genetics and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

5 Division of Medical Genetics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

4 Children's Hospitals and Clinics of Minnesota, Minneapolis, MN, USA.3 Center for Human Genetics and Department of Genetics and Genome Sciences, University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, OH, USA.Joseph's University Hospital, Paterson, NJ, USA. 1 Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.